Item Type | Name |
Concept
|
Adjuvants, Immunologic
|
Concept
|
Angiotensin-Converting Enzyme Inhibitors
|
Concept
|
Immunoglobulin M
|
Concept
|
Immunogenetics
|
Concept
|
Dose-Response Relationship, Immunologic
|
Concept
|
Cytotoxicity, Immunologic
|
Concept
|
Cytotoxicity Tests, Immunologic
|
Concept
|
Enzyme Inhibitors
|
Concept
|
Immunologic Factors
|
Concept
|
Dose-Response Relationship, Drug
|
Concept
|
Immune Tolerance
|
Concept
|
Immunotherapy
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
Concept
|
Immunity, Cellular
|
Concept
|
Immunoglobulin E
|
Concept
|
Immunocompetence
|
Concept
|
Immunoglobulin Isotypes
|
Concept
|
Immunohistochemistry
|
Concept
|
Immunoglobulin G
|
Concept
|
Immunization, Passive
|
Concept
|
Immunoenzyme Techniques
|
Concept
|
Receptors, Immunologic
|
Concept
|
Immunization
|
Concept
|
Immunoglobulin Class Switching
|
Concept
|
Reverse Transcriptase Inhibitors
|
Concept
|
Immunotherapy, Adoptive
|
Concept
|
Immunotherapy, Active
|
Concept
|
Receptors, Polymeric Immunoglobulin
|
Concept
|
Angiogenesis Inhibitors
|
Concept
|
Cyclooxygenase 2 Inhibitors
|
Concept
|
Immunogenetic Phenomena
|
Concept
|
Aromatase Inhibitors
|
Concept
|
Chromatin Immunoprecipitation
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p16
|
Concept
|
Hydroxymethylglutaryl-CoA Reductase Inhibitors
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p21
|
Concept
|
Structure-Activity Relationship
|
Concept
|
Inhibitor of Differentiation Protein 2
|
Concept
|
Immunoprecipitation
|
Concept
|
Immunoblotting
|
Concept
|
Monitoring, Immunologic
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p15
|
Concept
|
Immunoglobulins, Intravenous
|
Concept
|
Inhibitory Concentration 50
|
Concept
|
Cell Cycle Checkpoints
|
Concept
|
G1 Phase Cell Cycle Checkpoints
|
Concept
|
TNF-Related Apoptosis-Inducing Ligand
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p27
|
Concept
|
vpr Gene Products, Human Immunodeficiency Virus
|
Concept
|
Immunity, Innate
|
Concept
|
Immunoglobulins
|
Concept
|
Immunophenotyping
|
Concept
|
Protein Kinase Inhibitors
|
Concept
|
Enzyme-Linked Immunospot Assay
|
Academic Article
|
The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
|
Academic Article
|
Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
|
Academic Article
|
Ring finger protein 43 as a new target for cancer immunotherapy.
|
Academic Article
|
Implication of allelic polymorphism of osteopontin in the development of lupus nephritis in MRL/lpr mice.
|
Academic Article
|
Association of VKORC1 and CYP2C9 polymorphisms with warfarin dose requirements in Japanese patients.
|
Academic Article
|
Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells.
|
Academic Article
|
Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients.
|
Academic Article
|
Genetically manipulated human embryonic stem cell-derived dendritic cells with immune regulatory function.
|
Academic Article
|
Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers.
|
Academic Article
|
Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
|
Academic Article
|
A model of prediction system for adverse cardiovascular reactions by calcineurin inhibitors among patients with renal transplants using gene-based single-nucleotide polymorphisms.
|
Academic Article
|
HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients.
|
Academic Article
|
Expression of novel molecules, MICAL2-PV (MICAL2 prostate cancer variants), increases with high Gleason score and prostate cancer progression.
|
Academic Article
|
Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression.
|
Academic Article
|
Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients.
|
Academic Article
|
Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors.
|
Academic Article
|
Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.
|
Academic Article
|
Possible involvement of NEDD4 in keloid formation; its critical role in fibroblast proliferation and collagen production.
|
Academic Article
|
ADAM8 as a novel serological and histochemical marker for lung cancer.
|
Academic Article
|
Should CYP2D6 inhibitors be administered in conjunction with tamoxifen?
|
Academic Article
|
Evaluation of CYP2D6 and efficacy of tamoxifen and raloxifene in women treated for breast cancer chemoprevention: results from the NSABP P1 and P2 clinical trials.
|
Academic Article
|
Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.
|
Academic Article
|
Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.
|
Academic Article
|
Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.
|
Academic Article
|
Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
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Academic Article
|
Serum estradiol should be monitored not only during the peri-menopausal period but also the post-menopausal period at the time of aromatase inhibitor administration.
|
Academic Article
|
A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.
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Academic Article
|
Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression.
|
Academic Article
|
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
|
Academic Article
|
CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans.
|
Academic Article
|
Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA.
|
Academic Article
|
Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.
|
Academic Article
|
Combined immunotherapy with low-dose IL-2 plus IFN-alpha for metastatic renal cell carcinoma: survival benefit for selected patients with lung metastasis and serum sodium level.
|
Academic Article
|
Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells.
|
Academic Article
|
Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population.
|
Academic Article
|
Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics.
|
Academic Article
|
A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
|
Academic Article
|
Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.
|
Academic Article
|
Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy.
|
Academic Article
|
Inference from the relationships between linkage disequilibrium and allele frequency distributions of 240 candidate SNPs in 109 drug-related genes in four Asian populations.
|
Academic Article
|
Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4.
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Academic Article
|
Similarity of the allele frequency and linkage disequilibrium pattern of single nucleotide polymorphisms in drug-related gene loci between Thai and northern East Asian populations: implications for tagging SNP selection in Thais.
|
Academic Article
|
[A phase I study of combination-therapy with gemcitabine and epitope peptides derived from human vascular endothelial growth factor receptor for unresectable or recurrent pancreas cancer].
|
Academic Article
|
Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
|
Academic Article
|
Involvement of C12orf32 overexpression in breast carcinogenesis.
|
Academic Article
|
Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
|
Academic Article
|
Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.
|
Academic Article
|
Functional haplotypes of IL-12B are associated with childhood atopic asthma.
|
Academic Article
|
Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.
|
Academic Article
|
Comparative profiling of serum glycoproteome by sequential purification of glycoproteins and 2-nitrobenzensulfenyl (NBS) stable isotope labeling: a new approach for the novel biomarker discovery for cancer.
|
Academic Article
|
Association study of 71 European Crohn's disease susceptibility loci in a Japanese population.
|
Academic Article
|
Regulation of protein Citrullination through p53/PADI4 network in DNA damage response.
|
Academic Article
|
Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells.
|
Academic Article
|
Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
|
Academic Article
|
EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth.
|
Academic Article
|
Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.
|
Academic Article
|
Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
|
Academic Article
|
Quantitative structural characterization of local N-glycan microheterogeneity in therapeutic antibodies by energy-resolved oxonium ion monitoring.
|
Academic Article
|
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
|
Academic Article
|
Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
|
Academic Article
|
Stanniocalcin 2 overexpression in castration-resistant prostate cancer and aggressive prostate cancer.
|
Academic Article
|
MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells.
|
Academic Article
|
A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities.
|
Academic Article
|
Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome.
|
Academic Article
|
Involvement of G-patch domain containing 2 overexpression in breast carcinogenesis.
|
Academic Article
|
Overexpression of the potential kinase serine/ threonine/tyrosine kinase 1 (STYK 1) in castration-resistant prostate cancer.
|
Academic Article
|
Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells.
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Academic Article
|
TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
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Academic Article
|
Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia.
|
Academic Article
|
Identification of a functional variant in the MICA promoter which regulates MICA expression and increases HCV-related hepatocellular carcinoma risk.
|
Academic Article
|
Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer.
|
Academic Article
|
Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism.
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Academic Article
|
Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells.
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Academic Article
|
Cancer peptide vaccine therapy developed from oncoantigens identified through genome-wide expression profile analysis for bladder cancer.
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Academic Article
|
Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
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Academic Article
|
Seven new loci associated with age-related macular degeneration.
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Academic Article
|
Pathway analysis of genome-wide data improves warfarin dose prediction.
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Academic Article
|
Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.
|
Academic Article
|
p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway.
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Academic Article
|
Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair.
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Academic Article
|
Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.
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Academic Article
|
Over-expression of cysteine proteinase inhibitor cystatin 6 promotes pancreatic cancer growth.
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Academic Article
|
Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.
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Academic Article
|
The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene.
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Academic Article
|
Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy.
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Academic Article
|
Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles.
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Academic Article
|
Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839).
|
Academic Article
|
Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR.
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Academic Article
|
Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.
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Academic Article
|
In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy.
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Academic Article
|
Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125).
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Academic Article
|
WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck.
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Academic Article
|
p53RDL1 regulates p53-dependent apoptosis.
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Academic Article
|
Host molecular defense mechanisms against Chlamydophila pneumoniae and genetic studies of immune-response-related genes in asthma.
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Academic Article
|
Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells.
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Academic Article
|
Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
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Academic Article
|
Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.
|
Academic Article
|
Identification of promiscuous KIF20A long peptides bearing both CD4+ and CD8+ T-cell epitopes: KIF20A-specific CD4+ T-cell immunity in patients with malignant tumor.
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Academic Article
|
Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis.
|
Academic Article
|
Microarray analysis of gene-expression profiles in diffuse large B-cell lymphoma: identification of genes related to disease progression.
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Academic Article
|
Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis.
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Academic Article
|
Phase II clinical trial of multiple peptide vaccination for advanced head and neck cancer patients revealed induction of immune responses and improved OS.
|
Academic Article
|
Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema.
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Academic Article
|
Cancer vaccines.
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Academic Article
|
[Phase I study of combination therapy with peptide vaccine and anti-cancer drug for colorectal cancer].
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Academic Article
|
Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker.
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Academic Article
|
Genome-wide analysis of gene expression in human intrahepatic cholangiocarcinoma.
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Academic Article
|
Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.
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Academic Article
|
PCOTH, a novel gene overexpressed in prostate cancers, promotes prostate cancer cell growth through phosphorylation of oncoprotein TAF-Ibeta/SET.
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Academic Article
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Increases of amphiregulin and transforming growth factor-alpha in serum as predictors of poor response to gefitinib among patients with advanced non-small cell lung cancers.
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Academic Article
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Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.
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Academic Article
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Therapeutic potential of antibodies against FZD 10, a cell-surface protein, for synovial sarcomas.
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Academic Article
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Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.
|
Academic Article
|
Relationship between smoking and multiple colorectal cancers in patients with Japanese Lynch syndrome: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
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Academic Article
|
WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
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Academic Article
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Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics.
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Academic Article
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A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis.
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Academic Article
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ESE-3, an Ets family transcription factor, is up-regulated in cellular senescence.
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Academic Article
|
Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population.
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Academic Article
|
A functional polymorphism in IL-18 is associated with severity of bronchial asthma.
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Academic Article
|
Identification of immunoglobulin superfamily 11 (IGSF11) as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas.
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Academic Article
|
A novel tumor-associated antigen, cell division cycle 45-like can induce cytotoxic T-lymphocytes reactive to tumor cells.
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Academic Article
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A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
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Academic Article
|
Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer.
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Academic Article
|
Prevalence of allergic rhinitis and sensitization to common aeroallergens in a Japanese population.
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Academic Article
|
No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations.
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Academic Article
|
Inhibition of tumor growth through suppression of angiogenesis by brain-specific angiogenesis inhibitor 1 gene transfer in murine renal cell carcinoma.
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Academic Article
|
Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
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Academic Article
|
Japanese single nucleotide polymorphism database for 267 possible drug-related genes.
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Academic Article
|
Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.
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Academic Article
|
Radioimmunotherapy of human synovial sarcoma using a monoclonal antibody against FZD10.
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Academic Article
|
Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.
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Academic Article
|
Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma.
|
Academic Article
|
Enhanced SMYD3 expression is essential for the growth of breast cancer cells.
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Academic Article
|
Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.
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Academic Article
|
Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B.
|
Academic Article
|
A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population.
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Academic Article
|
Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
|
Academic Article
|
The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
|
Academic Article
|
Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor kappaB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure.
|
Academic Article
|
Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target.
|
Academic Article
|
Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.
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Academic Article
|
VAV3 mediates resistance to breast cancer endocrine therapy.
|
Academic Article
|
The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
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Academic Article
|
Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.
|
Academic Article
|
A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome.
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Academic Article
|
Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray.
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Academic Article
|
Identification of SPARC as a candidate target antigen for immunotherapy of various cancers.
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Academic Article
|
Serial analysis of gene expression in progressing and regressing mouse tumors implicates the involvement of RANTES and TARC in antitumor immune responses.
|
Academic Article
|
Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis.
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Academic Article
|
Functional impact of IgA nephropathy-associated selectin gene haplotype on leukocyte-endothelial interaction.
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Academic Article
|
The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).
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Academic Article
|
Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers.
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Academic Article
|
Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers.
|
Academic Article
|
Reevaluation of a lectin antibody ELISA kit for measuring fucosylated haptoglobin in various conditions.
|
Academic Article
|
Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy.
|
Academic Article
|
An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway.
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Academic Article
|
FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.
|
Academic Article
|
Large-scale single-nucleotide polymorphism (SNP) and haplotype analyses, using dense SNP Maps, of 199 drug-related genes in 752 subjects: the analysis of the association between uncommon SNPs within haplotype blocks and the haplotypes constructed with haplotype-tagging SNPs.
|
Academic Article
|
PDZ-binding kinase/T-LAK cell-originated protein kinase, a putative cancer/testis antigen with an oncogenic activity in breast cancer.
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Academic Article
|
TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis.
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Academic Article
|
Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor.
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Academic Article
|
Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome.
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Academic Article
|
Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations.
|
Academic Article
|
DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1 in renal cell carcinomas.
|
Academic Article
|
SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells.
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Academic Article
|
PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents.
|
Academic Article
|
T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia.
|
Academic Article
|
Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer.
|
Academic Article
|
Overexpressed P-cadherin/CDH3 promotes motility of pancreatic cancer cells by interacting with p120ctn and activating rho-family GTPases.
|
Academic Article
|
Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
|
Academic Article
|
HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL.
|
Academic Article
|
Identification of CDCA1-derived long peptides bearing both CD4+ and CD8+ T-cell epitopes: CDCA1-specific CD4+ T-cell immunity in cancer patients.
|
Academic Article
|
Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.
|
Academic Article
|
Germline PARP4 mutations in patients with primary thyroid and breast cancers.
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Academic Article
|
Importance of immunopharmacogenomics in cancer treatment: Patient selection and monitoring for immune checkpoint antibodies.
|
Academic Article
|
Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10: therapeutic efficacy largely depends on radiosensitivity.
|
Academic Article
|
Retraction. Cloning and expression of soluble recombinant human esophageal cancer-related gene 4 protein and its inhibitory effect on tumor growth in vitro and in vivo in esophageal carcinoma.
|
Academic Article
|
Multicenter, phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens.
|
Academic Article
|
Toxoplasma gondii exploits UHRF1 and induces host cell cycle arrest at G2 to enable its proliferation.
|
Academic Article
|
Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population.
|
Academic Article
|
Megakaryocyte potentiating factor as a tumor marker of malignant pleural mesothelioma: evaluation in comparison with mesothelin.
|
Academic Article
|
From cancer genomics to thoracic oncology: discovery of new biomarkers and therapeutic targets for lung and esophageal carcinoma.
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Academic Article
|
The current and future applications of immunopharmacogenomics.
|
Academic Article
|
Serum tumor antigen REG4 as a diagnostic biomarker in pancreatic ductal adenocarcinoma.
|
Academic Article
|
Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
|
Academic Article
|
Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
|
Academic Article
|
Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With ERBB Alterations.
|
Academic Article
|
Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors.
|
Academic Article
|
Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
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Academic Article
|
Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
|
Academic Article
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Anti-myeloma activity of MELK inhibitor OTS167: effects on drug-resistant myeloma cells and putative myeloma stem cell replenishment of malignant plasma cells.
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Academic Article
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p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1.
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Academic Article
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The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy.
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Pharmacogenomics and drug toxicity.
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Academic Article
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Effective induction of cytotoxic T cells recognizing an epitope peptide derived from hypoxia-inducible protein 2 (HIG2) in patients with metastatic renal cell carcinoma.
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Cancer Precision Medicine: From Cancer Screening to Drug Selection and Personalized Immunotherapy.
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Academic Article
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T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer.
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Diaminopyridine-based potent and selective mps1 kinase inhibitors binding to an unusual flipped-Peptide conformation.
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Academic Article
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WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck.
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Academic Article
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Host cell-specific effects of lentiviral accessory proteins on the eukaryotic cell cycle progression.
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Academic Article
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TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer.
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Academic Article
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WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.
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Academic Article
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Identification of immunogenic LY6K long peptide encompassing both CD4+ and CD8+ T-cell epitopes and eliciting CD4+ T-cell immunity in patients with malignant disease.
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Academic Article
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A clinical trial of multiple peptides vaccination for advanced head and neck cancer patients induced immune responses and prolonged OS.
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Academic Article
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Statin use and all-cause and cancer mortality: BioBank Japan cohort.
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Academic Article
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Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.
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Academic Article
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Integrated analysis of somatic mutations and immune microenvironment in malignant pleural mesothelioma.
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Academic Article
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Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer.
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Academic Article
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Multiple therapeutic peptide vaccines for patients with advanced gastric cancer.
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Academic Article
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Phase I clinical trial of cell division associated 1 (CDCA1) peptide vaccination for castration resistant prostate cancer.
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Academic Article
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Characterization of the T-Cell Receptor Repertoire and Immune Microenvironment in Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck.
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Academic Article
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Integrated analysis of somatic mutations and immune microenvironment of multiple regions in breast cancers.
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Academic Article
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Characterization of the cryoablation-induced immune response in kidney cancer patients.
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Academic Article
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Activation of Th1 Immunity within the Tumor Microenvironment Is Associated with Clinical Response to Lenalidomide in Chronic Lymphocytic Leukemia.
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Academic Article
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Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor-Engineered T Cells for Ovarian Cancer.
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Academic Article
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Integrated analysis of somatic mutations and immune microenvironment of multiple regions in breast cancers.
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Academic Article
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WT1 peptide vaccine in Montanide in contrast to poly ICLC, is able to induce WT1-specific immune response with TCR clonal enrichment in myeloid leukemia.
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Academic Article
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The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.
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Academic Article
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A pilot study of durvalumab and tremelimumab and immunogenomic dynamics in metastatic breast cancer.
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Academic Article
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A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors.
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Academic Article
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Immunotherapy with cancer peptides in combination with intravesical bacillus Calmette-Guerin for patients with non-muscle invasive bladder cancer.
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Academic Article
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Phase I Study of Multiple Epitope Peptide Vaccination in Patients With Recurrent or Persistent Cervical Cancer.
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Academic Article
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Development of novel SUV39H2 inhibitors that exhibit growth suppressive effects in mouse xenograft models and regulate the phosphorylation of H2AX.
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Immunoglobulin profiling identifies unique signatures in patients with Kawasaki disease during intravenous immunoglobulin treatment.
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Academic Article
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The era of immunogenomics/immunopharmacogenomics.
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Academic Article
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The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck.
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Academic Article
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Immunopharmacogenomics towards personalized cancer immunotherapy targeting neoantigens.
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Academic Article
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Characterization of the B-cell receptor repertoires in peanut allergic subjects undergoing oral immunotherapy.
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Academic Article
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A first-in-human study investigating biodistribution, safety and recommended dose of a new radiolabeled MAb targeting FZD10 in metastatic synovial sarcoma patients.
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Academic Article
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Identification of neoantigen-specific T cells and their targets: implications for immunotherapy of head and neck squamous cell carcinoma.
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Academic Article
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The road map of cancer precision medicine with the innovation of advanced cancer detection technology and personalized immunotherapy.
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Academic Article
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Immune profiles in primary squamous cell carcinoma of the head and neck.
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Academic Article
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Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.
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Academic Article
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Dose escalation prophylactic donor lymphocyte infusion after T-cell depleted matched related donor allogeneic hematopoietic cell transplantation is feasible and results in higher donor chimerism, faster immune re-constitution, and prolonged progression-free survival.
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Academic Article
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Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.
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Academic Article
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Bioinformatic prediction of potential T cell epitopes for SARS-Cov-2.
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Academic Article
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Intranodal Administration of Neoantigen Peptide-loaded Dendritic Cell Vaccine Elicits Epitope-specific T Cell Responses and Clinical Effects in a Patient with Chemorefractory Ovarian Cancer with Malignant Ascites.
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Academic Article
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CD8 lymphocytes in tumors and nonsynonymous mutational load correlate with prognosis of bladder cancer patients treated with immune checkpoint inhibitors.
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Academic Article
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Clinicopathologic significance of protein lysine methyltransferases in cancer.
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Academic Article
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Phase II Adjuvant Cancer-specific Vaccine Therapy for Esophageal Cancer Patients Curatively Resected After Preoperative Therapy With Pathologically Positive Nodes; Possible Significance of Tumor Immune Microenvironment in its Clinical Effects.
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Academic Article
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Correction: Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
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Academic Article
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Anti-cancer immunotherapy using cancer-derived multiple epitope-peptides cocktail vaccination clinical studies in patients with refractory/persistent disease of uterine cervical cancer and ovarian cancer [phase 2].
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Academic Article
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Diversity in immunogenomics: the value and the challenge.
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Academic Article
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Generation of neoantigen-specific T cells for adoptive cell transfer for treating head and neck squamous cell carcinoma.
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Academic Article
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Neoantigens elicit T cell responses in breast cancer.
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Academic Article
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Immunogenomics in personalized cancer treatments.
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Academic Article
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Efficacy of Intranodal Neoantigen Peptide-pulsed Dendritic Cell Vaccine Monotherapy in Patients With Advanced Solid Tumors: A Retrospective Analysis.
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Academic Article
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Personalized immunotherapy in cancer precision medicine.
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Academic Article
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Contribution of pre-existing neoantigen-specific T cells to a durable complete response after tumor-pulsed dendritic cell vaccine plus nivolumab therapy in a patient with metastatic salivary duct carcinoma.
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Academic Article
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Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer.
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Academic Article
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Precision Medicine for Colorectal Cancer with Liquid Biopsy and Immunotherapy.
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Academic Article
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Serial circulating tumor DNA monitoring of CDK4/6 inhibitors response in metastatic breast cancer.
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Academic Article
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Lymphocytes in tumor-draining lymph nodes co-cultured with autologous tumor cells for adoptive cell therapy.
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Concept
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Autophagy-Related Proteins
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Concept
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NIMA-Related Kinases
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Concept
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Antineoplastic Agents, Immunological
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Concept
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Caspase Inhibitors
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Concept
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Drug-Related Side Effects and Adverse Reactions
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Concept
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Calcineurin Inhibitors
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Concept
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Cytochrome P-450 CYP2D6 Inhibitors
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Academic Article
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Treatment satisfaction with molidustat in CKD-related anemia in non-dialysis patients: a post-hoc analysis of two clinical trials.
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Academic Article
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Immunological analysis of hybrid neoantigen peptide encompassing class I/II neoepitope-pulsed dendritic cell vaccine.
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Academic Article
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Pharmacogenetic and clinical risk factors for bevacizumab-related gastrointestinal hemorrhage in prostate cancer patients treated on CALGB 90401 (Alliance).
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