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Item TypeName
Concept Adjuvants, Immunologic
Concept Angiotensin-Converting Enzyme Inhibitors
Concept Immunoglobulin M
Concept Immunogenetics
Concept Dose-Response Relationship, Immunologic
Concept Cytotoxicity, Immunologic
Concept Cytotoxicity Tests, Immunologic
Concept Enzyme Inhibitors
Concept Immunologic Factors
Concept Dose-Response Relationship, Drug
Concept Immune Tolerance
Concept Immunotherapy
Concept Enzyme-Linked Immunosorbent Assay
Concept Immunity, Cellular
Concept Immunoglobulin E
Concept Immunocompetence
Concept Immunoglobulin Isotypes
Concept Immunohistochemistry
Concept Immunoglobulin G
Concept Immunization, Passive
Concept Immunoenzyme Techniques
Concept Receptors, Immunologic
Concept Immunization
Concept Immunoglobulin Class Switching
Concept Reverse Transcriptase Inhibitors
Concept Immunotherapy, Adoptive
Concept Immunotherapy, Active
Concept Receptors, Polymeric Immunoglobulin
Concept Angiogenesis Inhibitors
Concept Cyclooxygenase 2 Inhibitors
Concept Immunogenetic Phenomena
Concept Aromatase Inhibitors
Concept Chromatin Immunoprecipitation
Concept Cyclin-Dependent Kinase Inhibitor p16
Concept Hydroxymethylglutaryl-CoA Reductase Inhibitors
Concept Cyclin-Dependent Kinase Inhibitor p21
Concept Structure-Activity Relationship
Concept Inhibitor of Differentiation Protein 2
Concept Immunoprecipitation
Concept Immunoblotting
Concept Monitoring, Immunologic
Concept Cyclin-Dependent Kinase Inhibitor p15
Concept Immunoglobulins, Intravenous
Concept Inhibitory Concentration 50
Concept Cell Cycle Checkpoints
Concept G1 Phase Cell Cycle Checkpoints
Concept TNF-Related Apoptosis-Inducing Ligand
Concept Cyclin-Dependent Kinase Inhibitor p27
Concept vpr Gene Products, Human Immunodeficiency Virus
Concept Immunity, Innate
Concept Immunoglobulins
Concept Immunophenotyping
Concept Protein Kinase Inhibitors
Concept Enzyme-Linked Immunospot Assay
Academic Article The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
Academic Article Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
Academic Article Ring finger protein 43 as a new target for cancer immunotherapy.
Academic Article Implication of allelic polymorphism of osteopontin in the development of lupus nephritis in MRL/lpr mice.
Academic Article Association of VKORC1 and CYP2C9 polymorphisms with warfarin dose requirements in Japanese patients.
Academic Article Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells.
Academic Article Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients.
Academic Article Genetically manipulated human embryonic stem cell-derived dendritic cells with immune regulatory function.
Academic Article Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers.
Academic Article Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
Academic Article A model of prediction system for adverse cardiovascular reactions by calcineurin inhibitors among patients with renal transplants using gene-based single-nucleotide polymorphisms.
Academic Article HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients.
Academic Article Expression of novel molecules, MICAL2-PV (MICAL2 prostate cancer variants), increases with high Gleason score and prostate cancer progression.
Academic Article Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression.
Academic Article Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients.
Academic Article Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors.
Academic Article Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.
Academic Article Possible involvement of NEDD4 in keloid formation; its critical role in fibroblast proliferation and collagen production.
Academic Article ADAM8 as a novel serological and histochemical marker for lung cancer.
Academic Article Should CYP2D6 inhibitors be administered in conjunction with tamoxifen?
Academic Article Evaluation of CYP2D6 and efficacy of tamoxifen and raloxifene in women treated for breast cancer chemoprevention: results from the NSABP P1 and P2 clinical trials.
Academic Article Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.
Academic Article Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.
Academic Article Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.
Academic Article Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
Academic Article Serum estradiol should be monitored not only during the peri-menopausal period but also the post-menopausal period at the time of aromatase inhibitor administration.
Academic Article A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.
Academic Article Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression.
Academic Article Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
Academic Article CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans.
Academic Article Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA.
Academic Article Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.
Academic Article Combined immunotherapy with low-dose IL-2 plus IFN-alpha for metastatic renal cell carcinoma: survival benefit for selected patients with lung metastasis and serum sodium level.
Academic Article Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells.
Academic Article Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population.
Academic Article Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics.
Academic Article A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
Academic Article Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.
Academic Article Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy.
Academic Article Inference from the relationships between linkage disequilibrium and allele frequency distributions of 240 candidate SNPs in 109 drug-related genes in four Asian populations.
Academic Article Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4.
Academic Article Similarity of the allele frequency and linkage disequilibrium pattern of single nucleotide polymorphisms in drug-related gene loci between Thai and northern East Asian populations: implications for tagging SNP selection in Thais.
Academic Article [A phase I study of combination-therapy with gemcitabine and epitope peptides derived from human vascular endothelial growth factor receptor for unresectable or recurrent pancreas cancer].
Academic Article Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
Academic Article Involvement of C12orf32 overexpression in breast carcinogenesis.
Academic Article Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
Academic Article Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.
Academic Article Functional haplotypes of IL-12B are associated with childhood atopic asthma.
Academic Article Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.
Academic Article Comparative profiling of serum glycoproteome by sequential purification of glycoproteins and 2-nitrobenzensulfenyl (NBS) stable isotope labeling: a new approach for the novel biomarker discovery for cancer.
Academic Article Association study of 71 European Crohn's disease susceptibility loci in a Japanese population.
Academic Article Regulation of protein Citrullination through p53/PADI4 network in DNA damage response.
Academic Article Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells.
Academic Article Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
Academic Article EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth.
Academic Article Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.
Academic Article Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
Academic Article Quantitative structural characterization of local N-glycan microheterogeneity in therapeutic antibodies by energy-resolved oxonium ion monitoring.
Academic Article Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
Academic Article Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
Academic Article Stanniocalcin 2 overexpression in castration-resistant prostate cancer and aggressive prostate cancer.
Academic Article MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells.
Academic Article A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities.
Academic Article Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome.
Academic Article Involvement of G-patch domain containing 2 overexpression in breast carcinogenesis.
Academic Article Overexpression of the potential kinase serine/ threonine/tyrosine kinase 1 (STYK 1) in castration-resistant prostate cancer.
Academic Article Critical roles of LGN/GPSM2 phosphorylation by PBK/TOPK in cell division of breast cancer cells.
Academic Article TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
Academic Article Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia.
Academic Article Identification of a functional variant in the MICA promoter which regulates MICA expression and increases HCV-related hepatocellular carcinoma risk.
Academic Article Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer.
Academic Article Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism.
Academic Article Involvement of the tubulin tyrosine ligase-like family member 4 polyglutamylase in PELP1 polyglutamylation and chromatin remodeling in pancreatic cancer cells.
Academic Article Cancer peptide vaccine therapy developed from oncoantigens identified through genome-wide expression profile analysis for bladder cancer.
Academic Article Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
Academic Article Seven new loci associated with age-related macular degeneration.
Academic Article Pathway analysis of genome-wide data improves warfarin dose prediction.
Academic Article Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.
Academic Article p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway.
Academic Article Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair.
Academic Article Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.
Academic Article Over-expression of cysteine proteinase inhibitor cystatin 6 promotes pancreatic cancer growth.
Academic Article Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.
Academic Article The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene.
Academic Article Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy.
Academic Article Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles.
Academic Article Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839).
Academic Article Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR.
Academic Article Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.
Academic Article In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy.
Academic Article Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125).
Academic Article WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck.
Academic Article p53RDL1 regulates p53-dependent apoptosis.
Academic Article Host molecular defense mechanisms against Chlamydophila pneumoniae and genetic studies of immune-response-related genes in asthma.
Academic Article Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells.
Academic Article Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
Academic Article Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.
Academic Article Identification of promiscuous KIF20A long peptides bearing both CD4+ and CD8+ T-cell epitopes: KIF20A-specific CD4+ T-cell immunity in patients with malignant tumor.
Academic Article Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis.
Academic Article Microarray analysis of gene-expression profiles in diffuse large B-cell lymphoma: identification of genes related to disease progression.
Academic Article Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis.
Academic Article Phase II clinical trial of multiple peptide vaccination for advanced head and neck cancer patients revealed induction of immune responses and improved OS.
Academic Article Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema.
Academic Article Cancer vaccines.
Academic Article [Phase I study of combination therapy with peptide vaccine and anti-cancer drug for colorectal cancer].
Academic Article Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker.
Academic Article Genome-wide analysis of gene expression in human intrahepatic cholangiocarcinoma.
Academic Article Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.
Academic Article PCOTH, a novel gene overexpressed in prostate cancers, promotes prostate cancer cell growth through phosphorylation of oncoprotein TAF-Ibeta/SET.
Academic Article Increases of amphiregulin and transforming growth factor-alpha in serum as predictors of poor response to gefitinib among patients with advanced non-small cell lung cancers.
Academic Article Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.
Academic Article Therapeutic potential of antibodies against FZD 10, a cell-surface protein, for synovial sarcomas.
Academic Article Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.
Academic Article Relationship between smoking and multiple colorectal cancers in patients with Japanese Lynch syndrome: a cross-sectional study conducted by the Japanese Society for Cancer of the Colon and Rectum.
Academic Article WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
Academic Article Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics.
Academic Article A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis.
Academic Article ESE-3, an Ets family transcription factor, is up-regulated in cellular senescence.
Academic Article Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population.
Academic Article A functional polymorphism in IL-18 is associated with severity of bronchial asthma.
Academic Article Identification of immunoglobulin superfamily 11 (IGSF11) as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas.
Academic Article A novel tumor-associated antigen, cell division cycle 45-like can induce cytotoxic T-lymphocytes reactive to tumor cells.
Academic Article A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
Academic Article Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer.
Academic Article Prevalence of allergic rhinitis and sensitization to common aeroallergens in a Japanese population.
Academic Article No association for Chinese HBV-related hepatocellular carcinoma susceptibility SNP in other East Asian populations.
Academic Article Inhibition of tumor growth through suppression of angiogenesis by brain-specific angiogenesis inhibitor 1 gene transfer in murine renal cell carcinoma.
Academic Article Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
Academic Article Japanese single nucleotide polymorphism database for 267 possible drug-related genes.
Academic Article Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.
Academic Article Radioimmunotherapy of human synovial sarcoma using a monoclonal antibody against FZD10.
Academic Article Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.
Academic Article Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma.
Academic Article Enhanced SMYD3 expression is essential for the growth of breast cancer cells.
Academic Article Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.
Academic Article Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B.
Academic Article A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population.
Academic Article Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
Academic Article The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
Academic Article Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1alpha and nuclear factor kappaB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure.
Academic Article Identification of TOMM34, which shows elevated expression in the majority of human colon cancers, as a novel drug target.
Academic Article Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.
Academic Article VAV3 mediates resistance to breast cancer endocrine therapy.
Academic Article The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
Academic Article Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.
Academic Article A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome.
Academic Article Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray.
Academic Article Identification of SPARC as a candidate target antigen for immunotherapy of various cancers.
Academic Article Serial analysis of gene expression in progressing and regressing mouse tumors implicates the involvement of RANTES and TARC in antitumor immune responses.
Academic Article Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis.
Academic Article Functional impact of IgA nephropathy-associated selectin gene haplotype on leukocyte-endothelial interaction.
Academic Article The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).
Academic Article Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers.
Academic Article Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers.
Academic Article Reevaluation of a lectin antibody ELISA kit for measuring fucosylated haptoglobin in various conditions.
Academic Article Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy.
Academic Article An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway.
Academic Article FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.
Academic Article Large-scale single-nucleotide polymorphism (SNP) and haplotype analyses, using dense SNP Maps, of 199 drug-related genes in 752 subjects: the analysis of the association between uncommon SNPs within haplotype blocks and the haplotypes constructed with haplotype-tagging SNPs.
Academic Article PDZ-binding kinase/T-LAK cell-originated protein kinase, a putative cancer/testis antigen with an oncogenic activity in breast cancer.
Academic Article TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis.
Academic Article Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor.
Academic Article Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome.
Academic Article Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations.
Academic Article DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1 in renal cell carcinomas.
Academic Article SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells.
Academic Article PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents.
Academic Article T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia.
Academic Article Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer.
Academic Article Overexpressed P-cadherin/CDH3 promotes motility of pancreatic cancer cells by interacting with p120ctn and activating rho-family GTPases.
Academic Article Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
Academic Article HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL.
Academic Article Identification of CDCA1-derived long peptides bearing both CD4+ and CD8+ T-cell epitopes: CDCA1-specific CD4+ T-cell immunity in cancer patients.
Academic Article Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.
Academic Article Germline PARP4 mutations in patients with primary thyroid and breast cancers.
Academic Article Importance of immunopharmacogenomics in cancer treatment: Patient selection and monitoring for immune checkpoint antibodies.
Academic Article Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10: therapeutic efficacy largely depends on radiosensitivity.
Academic Article Retraction. Cloning and expression of soluble recombinant human esophageal cancer-related gene 4 protein and its inhibitory effect on tumor growth in vitro and in vivo in esophageal carcinoma.
Academic Article Multicenter, phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens.
Academic Article Toxoplasma gondii exploits UHRF1 and induces host cell cycle arrest at G2 to enable its proliferation.
Academic Article Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population.
Academic Article Megakaryocyte potentiating factor as a tumor marker of malignant pleural mesothelioma: evaluation in comparison with mesothelin.
Academic Article From cancer genomics to thoracic oncology: discovery of new biomarkers and therapeutic targets for lung and esophageal carcinoma.
Academic Article The current and future applications of immunopharmacogenomics.
Academic Article Serum tumor antigen REG4 as a diagnostic biomarker in pancreatic ductal adenocarcinoma.
Academic Article Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
Academic Article Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
Academic Article Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With ERBB Alterations.
Academic Article Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors.
Academic Article Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
Academic Article Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
Academic Article Anti-myeloma activity of MELK inhibitor OTS167: effects on drug-resistant myeloma cells and putative myeloma stem cell replenishment of malignant plasma cells.
Academic Article p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1.
Academic Article The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy.
Academic Article Pharmacogenomics and drug toxicity.
Academic Article Effective induction of cytotoxic T cells recognizing an epitope peptide derived from hypoxia-inducible protein 2 (HIG2) in patients with metastatic renal cell carcinoma.
Academic Article Cancer Precision Medicine: From Cancer Screening to Drug Selection and Personalized Immunotherapy.
Academic Article T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer.
Academic Article Diaminopyridine-based potent and selective mps1 kinase inhibitors binding to an unusual flipped-Peptide conformation.
Academic Article WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck.
Academic Article Host cell-specific effects of lentiviral accessory proteins on the eukaryotic cell cycle progression.
Academic Article TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer.
Academic Article WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.
Academic Article Identification of immunogenic LY6K long peptide encompassing both CD4+ and CD8+ T-cell epitopes and eliciting CD4+ T-cell immunity in patients with malignant disease.
Academic Article A clinical trial of multiple peptides vaccination for advanced head and neck cancer patients induced immune responses and prolonged OS.
Academic Article Statin use and all-cause and cancer mortality: BioBank Japan cohort.
Academic Article Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.
Academic Article Integrated analysis of somatic mutations and immune microenvironment in malignant pleural mesothelioma.
Academic Article Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer.
Academic Article Multiple therapeutic peptide vaccines for patients with advanced gastric cancer.
Academic Article Phase I clinical trial of cell division associated 1 (CDCA1) peptide vaccination for castration resistant prostate cancer.
Academic Article Characterization of the T-Cell Receptor Repertoire and Immune Microenvironment in Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck.
Academic Article Integrated analysis of somatic mutations and immune microenvironment of multiple regions in breast cancers.
Academic Article Characterization of the cryoablation-induced immune response in kidney cancer patients.
Academic Article Activation of Th1 Immunity within the Tumor Microenvironment Is Associated with Clinical Response to Lenalidomide in Chronic Lymphocytic Leukemia.
Academic Article Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor-Engineered T Cells for Ovarian Cancer.
Academic Article Integrated analysis of somatic mutations and immune microenvironment of multiple regions in breast cancers.
Academic Article WT1 peptide vaccine in Montanide in contrast to poly ICLC, is able to induce WT1-specific immune response with TCR clonal enrichment in myeloid leukemia.
Academic Article The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.
Academic Article A pilot study of durvalumab and tremelimumab and immunogenomic dynamics in metastatic breast cancer.
Academic Article A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors.
Academic Article Immunotherapy with cancer peptides in combination with intravesical bacillus Calmette-Guerin for patients with non-muscle invasive bladder cancer.
Academic Article Phase I Study of Multiple Epitope Peptide Vaccination in Patients With Recurrent or Persistent Cervical Cancer.
Academic Article Development of novel SUV39H2 inhibitors that exhibit growth suppressive effects in mouse xenograft models and regulate the phosphorylation of H2AX.
Academic Article Immunoglobulin profiling identifies unique signatures in patients with Kawasaki disease during intravenous immunoglobulin treatment.
Academic Article The era of immunogenomics/immunopharmacogenomics.
Academic Article The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck.
Academic Article Immunopharmacogenomics towards personalized cancer immunotherapy targeting neoantigens.
Academic Article Characterization of the B-cell receptor repertoires in peanut allergic subjects undergoing oral immunotherapy.
Academic Article A first-in-human study investigating biodistribution, safety and recommended dose of a new radiolabeled MAb targeting FZD10 in metastatic synovial sarcoma patients.
Academic Article Identification of neoantigen-specific T cells and their targets: implications for immunotherapy of head and neck squamous cell carcinoma.
Academic Article The road map of cancer precision medicine with the innovation of advanced cancer detection technology and personalized immunotherapy.
Academic Article Immune profiles in primary squamous cell carcinoma of the head and neck.
Academic Article Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.
Academic Article Dose escalation prophylactic donor lymphocyte infusion after T-cell depleted matched related donor allogeneic hematopoietic cell transplantation is feasible and results in higher donor chimerism, faster immune re-constitution, and prolonged progression-free survival.
Academic Article Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.
Academic Article Bioinformatic prediction of potential T cell epitopes for SARS-Cov-2.
Academic Article Intranodal Administration of Neoantigen Peptide-loaded Dendritic Cell Vaccine Elicits Epitope-specific T Cell Responses and Clinical Effects in a Patient with Chemorefractory Ovarian Cancer with Malignant Ascites.
Academic Article CD8 lymphocytes in tumors and nonsynonymous mutational load correlate with prognosis of bladder cancer patients treated with immune checkpoint inhibitors.
Academic Article Clinicopathologic significance of protein lysine methyltransferases in cancer.
Academic Article Phase II Adjuvant Cancer-specific Vaccine Therapy for Esophageal Cancer Patients Curatively Resected After Preoperative Therapy With Pathologically Positive Nodes; Possible Significance of Tumor Immune Microenvironment in its Clinical Effects.
Academic Article Correction: Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
Academic Article Anti-cancer immunotherapy using cancer-derived multiple epitope-peptides cocktail vaccination clinical studies in patients with refractory/persistent disease of uterine cervical cancer and ovarian cancer [phase 2].
Academic Article Diversity in immunogenomics: the value and the challenge.
Academic Article Generation of neoantigen-specific T cells for adoptive cell transfer for treating head and neck squamous cell carcinoma.
Academic Article Neoantigens elicit T cell responses in breast cancer.
Academic Article Immunogenomics in personalized cancer treatments.
Academic Article Efficacy of Intranodal Neoantigen Peptide-pulsed Dendritic Cell Vaccine Monotherapy in Patients With Advanced Solid Tumors: A Retrospective Analysis.
Academic Article Personalized immunotherapy in cancer precision medicine.
Academic Article Contribution of pre-existing neoantigen-specific T cells to a durable complete response after tumor-pulsed dendritic cell vaccine plus nivolumab therapy in a patient with metastatic salivary duct carcinoma.
Academic Article Established fibrous peritoneal metastasis in an immunocompetent mouse model similar to clinical immune microenvironment of gastric cancer.
Academic Article Precision Medicine for Colorectal Cancer with Liquid Biopsy and Immunotherapy.
Academic Article Serial circulating tumor DNA monitoring of CDK4/6 inhibitors response in metastatic breast cancer.
Academic Article Lymphocytes in tumor-draining lymph nodes co-cultured with autologous tumor cells for adoptive cell therapy.
Concept Autophagy-Related Proteins
Concept NIMA-Related Kinases
Concept Antineoplastic Agents, Immunological
Concept Caspase Inhibitors
Concept Drug-Related Side Effects and Adverse Reactions
Concept Calcineurin Inhibitors
Concept Cytochrome P-450 CYP2D6 Inhibitors
Academic Article Treatment satisfaction with molidustat in CKD-related anemia in non-dialysis patients: a post-hoc analysis of two clinical trials.
Academic Article Immunological analysis of hybrid neoantigen peptide encompassing class I/II neoepitope-pulsed dendritic cell vaccine.
Academic Article Pharmacogenetic and clinical risk factors for bevacizumab-related gastrointestinal hemorrhage in prostate cancer patients treated on CALGB 90401 (Alliance).
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